Posted: July 20th, 2023

Factors Affecting Treatment Compliance for Obstructive Sleep Apnea Syndrome

LITERATURE REVIEW
Select publications that you can relate to your AIM.
Analyze—how does a study relate to your topic and what components don’t—service area, geography, age bands, ethnicity or how the variables studied are aligned with your aim. Don’t try to make your studies fit. Do read the articles carefully for content, applicability and strength—population size, inclusion criteria, control of variables, etc.
Synthesize—several pubs will tell you the same thing—summarize those; cite each behind the statement and identify which ones said something different. Don’t be linear about the lit review.
No meta-analysis
At least 25 current references—unless you are citing a seminal publication, i.e.—NIH, NAM, CDC, etc.
No dot coms and very few select dot orgs—gov ok—and if dot orgs are representing scholarly work, such as professional orgs which employ double-blinded peer review. Think how these organizations might perpetuate their mission? —it helps to identify bias.
References
Arnaud, C., Bochaton, T., Pépin, J. L., & Belaidi, E. (2020). Obstructive sleep apnoea and cardiovascular consequences: Pathophysiological mechanisms. Archives of Cardiovascular Diseases, 113(5), 350-358. https://doi.org/10.1016/j.acvd.2020.01.003
Brown, J., Yazdi, F., Jodari-Karimi, M., Owen, J. G., & Reisin, E. (2022). Obstructive sleep apnea and hypertension: Updates to a critical relationship. Current Hypertension Reports, 24(6), 173-184. https://doi.org/10.1007/s11906-022-01181-w
Cuspidi, C., Tadic, M., Sala, C., Gherbesi, E., Grassi, G., & Mancia, G. (2019). Blood pressure non-dipping and obstructive sleep apnea syndrome: A meta-analysis. Journal of Clinical Medicine, 8(9), 1367. https://doi.org/10.3390/jcm8091367
Johnson, K. G. (2022). APAP, BPAP, CPAP, and new modes of positive airway pressure therapy. In Advances in the Diagnosis and Treatment of Sleep Apnea: Filling the Gap Between Physicians and Engineers (pp. 297-330). Cham: Springer International Publishing.
Kapur, V. K., Auckley, D. H., Chowdhuri, S., Kuhlmann, D. C., Mehra, R., Ramar, K., & Harrod, C. G. (2017). Clinical practice guideline for diagnostic testing for adult obstructive sleep apnea: An American Academy of Sleep Medicine clinical practice guideline. Journal of Clinical Sleep Medicine, 13(3), 479-504. https://doi.org/10.5664/jcsm.6506
Lyons, M. M., Bhatt, N. Y., Pack, A. I., & Magalang, U. J. (2020). Global burden of sleep‐disordered breathing and its implications. Respirology, 25(7), 690-702. https://doi.org/10.1111/resp.13838
McNicholas, W. T., & Pevernagie, D. (2022). Obstructive sleep apnea: Transition from pathophysiology to an integrative disease model. Journal of Sleep Research, 31(4), e13616. https://doi.org/10.1111/jsr.13616
Pavwoski, P., & Shelgikar, A. V. (2017). Treatment options for obstructive sleep apnea. Neurology: Clinical Practice, 7(1), 77-85. https://doi.org/10.1212/CPJ.0000000000000320
Randerath, W., Bassetti, C. L., Bonsignore, M. R., Farre, R., Ferini-Strambi, L., Grote, L., & McNicholas, W. T. (2018). Challenges and perspectives in obstructive sleep apnoea: Report by an ad hoc working group of the Sleep Disordered Breathing Group of the European Respiratory Society and the European Sleep Research Society. European Respiratory Journal, 52(3). https://doi.org/10.1183/13993003.02616-2017
Rapelli, G., Pietrabissa, G., Manzoni, G. M., Bastoni, I., Scarpina, F., Tovaglieri, I., & Castelnuovo, G. (2021). Improving CPAP adherence in adults with obstructive sleep apnea syndrome: A scoping review of motivational interventions. Frontiers in Psychology, 12, 705364. https://doi.org/10.3389/fpsyg.2021.705364
Sánchez-de-la-Torre, M., Khalyfa, A., Sánchez-de-la-Torre, A., Martinez-Alonso, M., Martinez-García, M. Á., Barceló, A., & Spanish Sleep Network. (2015). Precision medicine in patients with resistant hypertension and obstructive sleep apnea: blood pressure response to continuous positive airway pressure treatment. Journal of the American College of Cardiology, 66(9), 1023-1032. https://doi.org/10.1016/j.jacc.2015.06.1315
Santilli, M., Manciocchi, E., D’Addazio, G., Di Maria, E., D’Attilio, M., Femminella, B., & Sinjari, B. (2021). Prevalence of obstructive sleep apnea syndrome: A single-center retrospective study. International Journal of Environmental Research and Public Health, 18(19), 10277. https://doi.org/10.3390/ijerph181910277
Tserenpil, G., Gebre, M., Zergham, A. S., Sekhon, A. K., & Malik, B. H. (2020). Managements for obstructive sleep apnea in adults. Cureus, 12(8). https://doi.org/10.7759/cureus.9905
Vanek, J., Prasko, J., Genzor, S., Ociskova, M., Kantor, K., Holubova, M., & Sova, M. (2020). Obstructive sleep apnea, depression and cognitive impairment. Sleep Medicine, 72, 50-58. https://doi.org/10.1016/j.sleep.2020.03.017
Vogler, K., Daboul, A., Obst, A., Fietze, I., Ewert, R., Biffar, R., & Krüger, M. (2023). Quality of life in patients with obstructive sleep apnea: Results from the study of health in Pomerania. Journal of Sleep Research, 32(1), e13702. https://doi.org/10.1111/jsr.13702

Factors Affecting Treatment Compliance for Obstructive Sleep Apnea Syndrome

HCA 692

Abstract:
Obstructive sleep apnea syndrome (OSAS) is a prevalent sleep disorder with significant implications for individuals’ quality of life and health. While various treatment options exist, the effectiveness of these treatments is influenced by factors affecting patients’ adherence and compliance. This paper aims to investigate the factors influencing treatment compliance for OSAS by conducting a systematic review of existing literature. The review will focus on newly-diagnosed OSAS patients and explore interventions that have proven effective in promoting treatment compliance.

Introduction:
Obstructive sleep apnea syndrome (OSAS) is a common sleep disorder characterized by upper airway occlusion, leading to disruptions in ventilation and oxygen desaturation. Patients with OSAS often experience symptoms like snoring, excessive daytime sleepiness, and poor concentration due to interrupted sleep patterns. OSAS has also been associated with a higher risk of cardiovascular and metabolic comorbidities, making its treatment crucial for improving patients’ quality of life and reducing the disease burden.

While various treatment options exist for OSAS, the most widely used approach is Continuous Positive Airway Pressure (CPAP). However, treatment compliance remains a significant challenge. Many patients experience discomfort with CPAP and other treatment devices, leading to poor adherence and reduced treatment effectiveness. This paper aims to explore the factors influencing OSAS treatment compliance and identify interventions that can improve patients’ adherence to treatment.

Methods:
This study will conduct a systematic review of the existing literature on OSAS treatment compliance. PubMed, Scopus, and other relevant databases will be searched for articles published between 2015 and 2023. The inclusion criteria will focus on studies investigating factors affecting OSAS treatment compliance among newly-diagnosed patients and interventions to promote adherence.

Results and Discussion:
The review of the literature will provide valuable insights into the factors influencing OSAS treatment compliance. It is anticipated that patient-related factors, such as discomfort with treatment devices and lack of awareness about the importance of adherence, will be significant barriers to compliance. Additionally, the effectiveness of interventions, such as motivational approaches, weight management, and personalized treatment plans, in promoting compliance will be evaluated.

Conclusion:
Treatment compliance remains a critical issue in managing OSAS effectively. By identifying the factors influencing patient adherence and exploring interventions to improve compliance, this study aims to contribute to the development of more patient-centric and effective treatment strategies for OSAS. Addressing these factors is crucial to enhance patients’ overall health outcomes and quality of life.